This study is about the utilization of preventive measure to prevent Neonatal sepsis by nurses in Selected Hospitals in Bulacan. The researcher aims to define the subject matter and further gives the factors that may aggravate the said topic. The research will tackle more of the medical implication and actions that may hasten the disease . In this paper, the researcher hopes to mask the medical profession that may alleviate or deteriorate the said topic. It is important for researcher to make the nursing profession transparent in this topic since it has direct effects on the promotion or prevention of the certain disease, although this paper does not suggest that medical personnel are the culprit of neonatal sepsis.in addition to the topic, the researchers had the opportunity to inculcate to the reader the means on how to prevent neonatal sepsis. In all these, the research is all based on gathered facts, both in literature and questionnairres. The researcher in all their effort made this research as objective as possible.